Special RepoRt

The 3rd European Science Foundation– University of Barcelona (ESF–UB) Conference in Biomedicine on Pharmacogenetics and Pharmacogenomics was held in Sant Feliu de Guixols, Spain, from 6–10 June 2010. It was focused on practical applications in routine medical practice [101]. When planning this conference 2 years ago, we thought it would be interesting to synthesize some knowledge gained in the field of pharmacogenetics and pharmacogenomics in the last 50 years, in order to identify the current pharmacogenetic/ pharmaco genomic tests that could be used in routine medical practice. Our aim was to determine, through daily discussions involving all participants, which pharmaco genetic information might be useful for patient therapy. In addition, we wanted to attempt to make some recommendations on which pharmacogenetic tests should be performed in routine medicine and decide what advice we might give to physicians regarding some of these pharmacogenetic/pharmaco genomic tests. The conference could not cover the whole field of pharmaco genetics/pharmaco genomics. Therefore, we limited the program to examples that we considered the most clinically relevant in the field of oncology, cardio vascular diseases, adverse drug reactions (ADRs) and organ transplantation. This choice is naturally subjective, excluding large parts of pharmaco genetics/ pharmaco genomics such as neuropsychopharmacology, pain, addiction and rheumatology. We present herein our conclusions on pharmacogenetic information that might be useful in ten clinical situations: guidance recommendations on which tests to be performed, and advice to physicians concerning these tests.